A 52-year-old woman presented with recurrent oral blood blisters. She had a history of thalassemia minor and idiopathic vulvar pruritus. She had also undergone a hysterectomy because of a leiomyoma. For the past 6 years, painful blood blisters had been occurring on the lateral borders of her tongue and buccal mucosa 8 to 10 times per year. The lesions ruptured in a few hours, leaving superficial ulcers that healed in 2 or 3 days. They were usually solitary but were sometimes multiple. The patient reported no other mucosal or skin lesions or any bleeding tendency. She had used a dental prosthesis for the last 11 years.
Domínguez JD, Rodríguez-Peralto JL, Iglesias L. Recurrent Oral Blood Blisters. Arch Dermatol. 1999;135(5):593-a-598. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-5-dof8025