Cases of leukocytoclastic vasculitis (LCV) induced by food additives are extremely rare.1- 3 We report a case of LCV presenting with purpuric lesions almost exclusively on upper body parts. In this case, none of the common causes of LCV could be found, but double-blind, placebo-controlled oral challenge testing (DPOC) with common food additives revealed sodium benzoate as the causative substance.
Vogt T, Landthaler M, Stolz W. Sodium Benzoate–Induced Acute Leukocytoclastic Vasculitis With Unusual Clinical Appearance. Arch Dermatol. 1999;135(6):726-727. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-6-dlt0699