Scar carcinoma (Marjolin ulcer), a rare complication of burns wounds,1 is generally considered to result from long-term local irritation and/or sunlight exposure. Microorganisms have not previously been associated with this disease. This report describes a recurrent scar carcinoma in an immunocompetent individual that was found to contain a novel human papillomavirus (HPV) DNA sequence.
Lee SH, Rose BR, Thompson CH, Cossart YE. A Novel Human Papillomavirus DNA Sequence Related to Epidermodysplasia Verruciformis–Associated Types Isolated From Recurrent Scar Carcinoma. Arch Dermatol. 1999;135(6):727-728. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-6-dlt0699