A 74-year-old white woman presented with a slowly growing tender plaque on her left palm. Despite repeated examinations by multiple physicians over the course of 10 years, a diagnosis was never made. Topical treatments with antifungal agents and steroid creams were ineffective. After complaining of intermittent bleeding and increasing pain and tenderness, the patient presented to the dermatology clinic, where a biopsy was performed. She had no history of irradiation, arsenic exposure, or repeated trauma to her palms. Furthermore, there was no family history of basal cell nevus syndrome.
Park JY, Parry EL. A Slowly Growing Tender Plaque of the Palm. Arch Dermatol. 1999;135(6):707-712. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-6-dof0699