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June 1999

Congenital Painful Pedal Mass

Arch Dermatol. 1999;135(6):707-b-712. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-6-dof0699

Neural fibrolipoma is a rare soft tissue neoplasm, with fewer than 100 cases reported since it was first described in the English literature in 1953.1 Other names that have been used for this entity include fibrolipomatous hamartoma of nerve, lipofibromatous hamartoma, intraneural lipoma, perineural lipoma, and macrodystrophia lipomatosa (when it is associated with macrodactyly).1 Neural fibrolipoma presents as a gradually expanding subcutaneous mass and may be accompanied by tenderness, decreased sensation, paresthesia, or compression neuropathy. Most patients present before the age of 30 years.1 The median nerve is affected in the vast majority of cases, but other sites reported include the ulnar, radial, and plantar nerves.2 Neural fibrolipomas are very rarely found in nerves of the toes.3 One third of patients with neural fibrolipoma have associated macrodactyly.3

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