My article dealt with problems of incomplete reporting of data and inappropriately defined end points. How can one compare cure statistics when, as Dr Elewski points out, "the definition of ‘cure' varies between studies"?
Elewski emphasizes the difficulties that may be encountered when treating toenail onychomycosis. Such difficulties make it imperative that treatment protocols use a clinically relevant, clearly defined end point. Dealing with difficult-to-treat disorders does not release investigators from their obligation to fully and accurately provide all their data.
Epstein E. A Full "Cure" for Onychomycosis Is Not Always Possible—Reply. Arch Dermatol. 1999;135(7):853. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-7-dlt0799