Bowen disease is a precancerous dermatosis that may occur on both exposed and unexposed skin. In recent studies, a relationship between genital Bowen disease and various types of human papillomavirus (HPV), especially the mucosal type, has been revealed. We report a case of genital Bowen disease in which HPV type 57b was detected by polymerase chain reaction.
A 66-year-old man had first noticed a small eruption on his penis about 10 years previously that had gradually enlarged with no symptomatic signs. Physical examination results revealed a flat-elevated, well-demarcated, brown-black plaque with a warty keratotic surface 43×37 mm in diameter on the dorsal aspect of his foreskin (Figure 1, top).
Ohnishi T, Kano R, Nakamura Y, Hasegawa A, Watanabe S. Genital Bowen Disease Associated With an Unusual Human Papillomavirus Type 57b. Arch Dermatol. 1999;135(7):858-859. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-7-dlt0799