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October 1999

Periorificial Dermatitis and Irritability in an Infant—Quiz Case

Author Affiliations
  • 1Medical University of South Carolina, Charleston (Dr Sahn), and Greenville Memorial Hospital, Greenville, SC (Dr Woodall)
Arch Dermatol. 1999;135(10):1267-1272. doi:10.1001/jamadermatol.58606

A 3½-month-old white boy presented with scaly, erythematous plaques on perioral and perianal skin and on the trunk and right thigh. The perioral eruption began 1 month before presentation and was treated with oral antibiotics and mupirocin ointment, without improvement. Two weeks later, a perianal eruption and diarrhea developed. Five days before presentation, an eruption developed on the thigh and trunk. The patient was born 5 weeks prematurely and weighed 2.5 kg at birth. He was totally breast-fed. At 3 months, he weighed 5.6 kg. He had been irritable and hard to console since birth, with no smiling and almost continuous crying while awake.

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