The objective of this survival study was to determine whether melanoma of the foot has a poorer prognosis than melanoma of the leg. The authors compared the survival probabilities of 119 patients with localized melanoma of the foot with those of 238 patients with localized melanoma of the leg; the groups were matched by age, sex, surgical group (wide excision or excision plus lymph node dissection), year of diagnosis, tumor thickness, and ulceration. The patient population of this study was derived from a combined data set of 1293 patients with leg lesions who were treated at the University of Alabama, Birmingham, and the Sydney Melanoma Unit in Australia.
Corona R. Does Localized Melanoma of the Foot Have a Poorer Prognosis Than Melanoma of the Leg?. Arch Dermatol. 1999;135(12):1529. doi:10.1001/archderm.135.12.1529