Malignant melanoma (MM) arising in burn scars is rarer than the classic form, with only about 22 cases reported in the literature.1 We report 3 new cases and the results of a literature review focusing on the promoting factors of this particular malignant transformation.
Three female patients, aged 57, 65, and 75 years, respectively, consulted us for tumoral lesions (2 thoracic and 1 abdominal) arising in scars from burns incurred 47, 59, and 70 years previously (Figure 1). The histologic diagnosis for the 2 younger patients was MM of nodular type 2 (Figure 2)and for the oldest patient, superficial spreading melanoma. After only surgical treatment, 2 patients remained alive and without disease after 45 and 54 months of follow-up, respectively; 1 died of metastatic disease 11 months after diagnosis.
Ghazi J, Hamouda B, Amor G, Emna E, Samira K, Amel BO, Khaled R. Melanoma Arising in Burn Scars: Report of 3 Observations and a Literature Review. Arch Dermatol. 1999;135(12):1551-a-1553. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-135-12-dlt1299