In a randomized trial published in the July issue of ARCHIVES, Ioannides1 et al compared the effectiveness of corticosteroids alone with a combination of corticosteroids and cyclosporine in 33 hospitalized patients with pemphigus. The authors clearly demonstrated that adding cyclosporine to a corticosteroid treatment regimen had no advantage over corticosteroids alone in the acute phase of the disease.
Vardy DA, Cohen AD. Cyclosporine Therapy Should Be Considered for Maintenance of Remission in Patients With Pemphigus. Arch Dermatol. 2001;137(4):505. doi: