SADICK AND Hudgins1 are to be congratulated on their efforts to establish, through scientific methods, the long-term viability of transplanted autologous adipocytes. They have endeavored to quantify, and in part they have taken a small step to confirm, the widely held belief that transplanted fat can survive as a material for soft tissue augmentation. However, of the 6 patients evaluated, only 1 showed the presence of transplanted adipocytes after 1 year using the measurement of fatty acid content as an indicator of graft survival. Although the persistence of transplanted fat in 1 patient is exciting, many physicians would agree that it is difficult to categorize these data as unequivocal proof that autologous fat transplantation (AFT) produces long-term soft tissue augmentation. Yet the data presented, and the conclusions reached by Sadick and Hudgins, raise interesting questions as to the current role of AFT and the paucity of available data to confirm the widely held belief that fat transplantation works and lasts.
Kaminer MS, Omura NE. Autologous Fat Transplantation. Arch Dermatol. 2001;137(6):812-814. doi:10-1001/pubs.Arch Dermatol.-ISSN-0003-987x-137-6-ded00019