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June 2001

Use of the 308-nm Excimer Laser for Postresurfacing Leukoderma

Arch Dermatol. 2001;137(6):824-825. doi:

Leukoderma is a common, late complication of carbon dioxide laser resurfacing1 and is usually very distressing to patients. Grimes et al2 recently reported a pilot study in which topical psoralen plus UV-A therapy induced moderate to excellent repigmentation in 71% of patients with postresurfacing hypopigmentation. Immunohistochemical staining with Fontana-Masson and Mel-5 revealed evidence of residual melanocytes and epidermal melanin.2

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