I appreciate your thoughtful comments about the Cutting Edge article by Itoh et al1 in the September issue of the ARCHIVES. I am in total agreement with your assessment that the patient's acne vulgaris would not have been considered intractable in the United States. However, the Cutting Edge is not only for therapies of last resort, but it is a forum for emerging therapies that may become alternatives to other established treatments. We accept for publication new therapies as well as novel uses of existing therapies. It is hoped that Cutting Edge articles will be thought-provoking and controversial and that they may lead to more controlled studies to rigorously assess the therapies presented. Judging from your letter, we have clearly succeeded in the former.
Hruza GJ. Bullous Pemphigoid Associated With Castleman Disease. Arch Dermatol. 2001;137(7):965-966. doi: