[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Off-Center Fold
July 2001

Palpable Purpura on the Extremities

Author Affiliations


Arch Dermatol. 2001;137(7):957-962. doi:

Microscopic examination revealed a dense dermal perivascular infiltrate with a predominance of neutrophils and extravasated red blood cells. Higher-power magnification demonstrated nuclear dust (karyorrhexis) and the presence of neutrophils and fibrin within vessel walls.

Leukocytoclastic vasculitis is a common cause of purpuric lesions on the extremities. Bacterial endocarditis should be considered, especially if the patient has a fever and an underlying heart murmur, because acute management of this life-threatening condition is required.

First Page Preview View Large
First page PDF preview
First page PDF preview