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September 2001

Propionibacterium acnes: An Indigenous Bacterium May Be Pathogenic in Several Cutaneous Disease States

Arch Dermatol. 2001;137(9):1250. doi:

We read with interest the article by Bachelez et al1 in which a pathological role of Propionibacterium acnes in lesions of sarcoidosis is supported by quantitative polymerase chain reaction studies of lymph nodes in affected patients. Interestingly, P acnes has been shown to be serologically and biochemically identical to Corynebacterium parvum, a potent stimulator of the reticuloendothelial system.2 Additionally, Propionibacterium species have been found within cholesterol gallstones by nested primer polymerase chain reaction studies,3 and an association with allergic alveolitis and pulmonary angiitis has been found by experimental intravenous challenge.4

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