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November 2001

Multiple Eruptive Angiofibromas of the Trunk: Case Report of a New Entity?

Arch Dermatol. 2001;137(11):1533-1535. doi:

Multiple angiofibromas of the face are a symptom of tuberous sclerosis complex (TSC) or multiple endocrine neoplasia type 1. Solitary angiofibromas may occur spontaneously. To our knowledge, the occurrence of multiple angiofibromas on the trunk, without other symptoms, has not been described. We describe an 18-year-old white man with multiple (>100) eruptive angiofibromas on his chest and back. He had no other symptoms of systemic disorders. The absence of hamartin and tuberin within the angiofibromas suggested that this disorder is associated with abnormal expression of TSC1 and TSC2 gene products.

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