THE SEARCH for an effective and safe therapy for bullous pemphigoid (BP) is important. Compared with other cutaneous disorders, BP has a relatively high morbidity and may occasionally be fatal. It most frequently affects the elderly, who are especially susceptible to the adverse effects of systemic drugs such as corticosteroids. The first-line agents that are used by most dermatologists are systemic corticosteroids. In mild cases of BP, there is a tendency to use potent topical steroids or anti-inflammatory agents other than corticosteroids, such as oral antibiotics, nicotinamide, or dapsone. In rare instances, nonsteroidal immunosuppressive therapy is instituted.
Mutasim DF. Treatment Considerations While Awaiting the Ideal Bullous Pemphigoid Trial. Arch Dermatol. 2002;138(3):404. doi:10.1001/archderm.138.3.404