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March 2002

Cutaneous Small Vessel Vasculitis: An Entity With Frequent Renal Involvement

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Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2002

Arch Dermatol. 2002;138(3):412-414. doi:10.1001/archderm.138.3.411

Cutaneous small vessel vasculitis (CSVV) affects vessels smaller than arteries, such as arterioles, venules, and capillaries of the skin. It is a condition that is usually characterized clinically by palpable purpura, predominantly involving the lower extremities, and histologically by leukocytoclastic vasculitis.1 Primary small vessel vasculitides that may induce injury to the kidney include Henoch-Schönlein purpura, cryoglobulinemic vasculitis, and necrotizing vasculitis associated with antineutrophilic cytoplasmic autoantibodies, such as microscopic polyangiitis and Wegener granulomatosis.2 Assessment of renal involvement is of principal importance for further evaluation of patients presenting to the dermatologist with CSVV.

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