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Off-Center Fold
April 2002

Alopecia, Hypohidrosis, and Ulcerations in a Man

Author Affiliations
 

MICHAEL E.MINGMD

Arch Dermatol. 2002;138(4):527-532. doi:10.1001/archderm.138.4.527

Histologic examination showed a dense lichenoid dermal infiltrate with marked epidermotropism of highly atypical, convoluted lymphocytes. Atypical lymphocytes surrounding and infiltrating the wall of small to medium-size vessels in the dermis and subcutaneous tissue were noted in the biopsy specimen from the area near an ulceration. There was epidermotropism into sweat glands, with epithelial proliferation and loss of the lumen. A biopsy specimen from the scalp showed perifollicular infiltrates of atypical lymphocytes with epidermotropism. These findings are consistent with mycosis fungoides.

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