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May 2002

Proptosis With Violaceous Dermal and Subcutaneous Skin Nodules in an Infant

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Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2002

Arch Dermatol. 2002;138(5):689-694. doi:10.1001/archderm.138.5.689

Light microscopy showed a very cellular tumor that was composed of undifferentiated round to oval tumor cells with darkly hyperchromatic nuclei and indistinct cytoplasm. The tumor cells showed a diffuse growth with no recognizable arrangement. Immunohistochemical staining revealed that the tumor cells were strongly positive for vimentin, desmin, and myoglobin and negative for epithelial membrane antigen, keratin, neuron-specific enolase, S100 protein, and leukocyte common antigen.

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