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June 2002

Segmental Lesions Are Not Always Agminated

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Arch Dermatol. 2002;138(6):838. doi:10.1001/archderm.138.6.838

In the July 2001 issue of the ARCHIVES, Marghoob et al1 describe agminated dysplastic nevi in a patient who had, in addition, numerous disseminated dysplastic and nondysplastic melanocytic nevi. The authors may be quite right in assuming that the agminated lesions, being superimposed on the disseminated, nonsegmental phenotype, resulted from loss of heterozygosity for one of the various genes responsible for the development of multiple melanocytic nevi.2

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