Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2002
The biopsy specimen demonstrated a well-circumscribed proliferation of irregular cords and small nests of basaloid cells with occasional keratinous cysts in a prominent desmoplastic stroma. There were also epidermal hyperplasia and areas of calcification with occasional foreign body granulomas.
Desmoplastic trichoepithelioma is a rare, benign adnexal tumor that usually presents as an asymptomatic, firm, annular plaque. It most commonly occurs on sun-exposed areas in middle-aged women, especially on the face. Occasionally, lesions may appear on the scalp, neck, and upper trunk area.1 Patients typically give a history of a single, slow-growing lesion that has been present for several years. The lesions are relatively small (<2 cm). There are typically no associated symptoms or family history of similar disease. Although the most frequent presentation is a plaque, desmoplastic trichoepithelioma has also been observed as aggregate annular lesions with a ring of papules in the periphery.2
Asymptomatic Annular Plaque of the Chin. Arch Dermatol. 2002;138(8):1091-1096. doi:10.1001/archderm.138.8.1091