The biopsy specimen revealed an intradermal benign neoplasm composed of spindle cells with blunt, vesicular nuclei arranged in interweaving fascicles. There were characteristic intracytoplasmic eosinophilic globules measuring approximately 5 to 9 µm in diameter.
The clinical and histologic findings led to a diagnosis of recurrent infantile digital fibromatosis. After being informed of the benign nature of these lesions, the patient's mother preferred conservative treatment with observation only.
Recurrent Nodules on the Feet of a Child. Arch Dermatol. 2002;138(9):1245-1250. doi:10.1001/archderm.138.9.1245