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Evidence-Based Dermatology: Research Commentary
December 2002

Systematic Review of Imiquimod for the Treatment of Genital Warts: All That Glitters Is Not Gold

Author Affiliations

MichaelBigbyMDRosamariaCoronaDSc, MDDamianoAbeniMD, MPHPaoloPaolo PasquiniMD, MPHMoysesSzkloMD, MPH, DrPHHywelWilliamsMD

Arch Dermatol. 2002;138(12):1599-1601. doi:10.1001/archderm.138.12.1599

Question: In immunocompetent patients with external genital warts, what are the benefits and the harms of imiquimod therapy?

Data Sources: Studies were identified through a search of MEDLINE (1966-2000), the Cochrane Library (issue 3, 2000), and PubMed (December 15, 2000). Reference lists of review articles were searched for additional trials, and the manufacturers of 5% imiquimod cream were asked about clinical trials. Authors of articles were not contacted for unpublished reports or for additional information from published reports. No restrictions to language were made.

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