We describe a patient who experienced systemic adverse effects after the injection of botulinum toxin type B (Myobloc) to treat palmar hyperhidrosis. The adverse effects included blurry vision, indigestion, and a severe dry throat associated with dysphagia. Although systemic adverse effects have been described in the medical literature after the use of botulinum toxin type B for the treatment of cervical dystonia, to our knowledge, it has never been described as being associated with the treatment of palmar hyperhidrosis.
Baumann LS, Halem ML. Systemic Adverse Effects After Botulinum Toxin Type B (Myobloc) Injections for the Treatment of Palmar Hyperhidrosis. Arch Dermatol. 2003;139(2):226. doi:10.1001/archderm.139.2.226