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February 2003

Violaceous Plaques in a Patient With Acquired Immunodeficiency Syndrome—Diagnosis

Arch Dermatol. 2003;139(2):215-220. doi:10.1001/archderm.139.2.215-b

Parakeratosis, acanthosis, and scattered dyskeratotic cells were seen in the epidermis. A dermal lichenoid lymphocytic infiltrate with occasional eosinophils and pigment incontinence were also present.

Treatment consisted of the use of topical 0.05% fluocinonide cream and a broad-spectrum sunscreen, sun avoidance, and discontinuation of sulfamethoxazole-trimethoprim therapy. The lesions slowly resolved over several weeks. Postinflammatory hyperpigmentation was noted at involved sites during the resolution phase.