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March 2003

Brownish Reticulate Maculopapular Eruption on the Flexures—Diagnosis

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Arch Dermatol. 2003;139(3):381-386. doi:10.1001/archderm.139.3.381-a

Histologic examination of the biopsy specimen showed a perivascular and interstitial mast cell infiltrate involving the papillary and middle dermis. The mast cells were round and oval, with abundant granular cytoplasm and a central nucleus. The cytoplasmic granules of the mast cells stained metachromatically with Giemsa stain (Figure 3). These findings were consistent with the diagnosis of cutaneous mastocytosis.

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