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April 2003

Solitary Nasal Ala Nodule in a Young Woman—Diagnosis

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Copyright 2003 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2003

Arch Dermatol. 2003;139(4):531-536. doi:10.1001/archderm.139.4.531-a

Histologic examination of the excised nodule showed a well-circumscribed, cellular, dermal nodule composed of spindled and epithelioid cells within a myxoid matrix. The cells were arranged in fascicles, with areas of plexiform compartmentalization. The epithelioid cells demonstrated bizarre cytologic atypia and pale eosinophilic cytoplasm. Rare mitoses were present. Immunohistochemical studies for S100 protein showed a very rare cell suggestive of weak positivity.

Three years after surgery there was still no evidence of recurrence.

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