VITILIGO IS an acquired pigmentary disorder, clinically characterized by the development of white macules caused by damage to melanocytes in the affected skin.1 The prevalence of the disease in the United States and Europe has been estimated at around 1%. Half of all patients develop the disease in childhood and adolescence before age 20 years, making vitiligo an important topic of pediatric dermatology.
Plettenberg H, Assmann T, Ruzicka T. Childhood Vitiligo and TacrolimusImmunomodulating Treatment for an Autoimmune Disease. Arch Dermatol. 2003;139(5):651-654. doi:10.1001/archderm.139.5.651