On microscopic examination, the epidermis was unremarkable. In the middermis, many histiocytes, often multinucleated, were noted in association with fragmentation of the elastic fibers, which was more obvious in sections stained with orcein (Figure 4). Fragments of elastic fibers were engulfed by multinucleated giant cells. There was no necrobiosis or excessive mucopolysaccharide deposition.
Large Annular Plaques on the Trunk and Arms—Diagnosis. Arch Dermatol. 2003;139(5):657-662. doi:10.1001/archderm.139.5.657-a