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June 2003

The Significance of Vascular Invasion in Primary Melanomas of Thin or Intermediate Thickness

Author Affiliations

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Arch Dermatol. 2003;139(6):809. doi:10.1001/archderm.139.6.809

In a recent letter entitled "An Inaccuracy in an Otherwise Solid Study," Dr A. Bernard Ackerman1 criticizes the statement by Kashani-Sabet et al2 that "the role of [vascular invasion] in the prognostic assessment of malignant melanoma has remained controversial." It is the view of Dr Ackerman and his associates that vascular invasion by any melanoma is "virtually equivalent to metastasis."1 He says that, except for a single statement in the literature saying that vascular invasion does "not influence prognosis significantly," he is unaware of any "statement to that effect anywhere."1

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