Although loss of heterozygosity (LOH) at the 9p22-21 and 1p36 regions, especially the D1S214 locus, has been established in cutaneous malignant melanomas (CMMs), refined deletional analyses of these regions are still lacking.1,2 Therefore, we analyzed 112 melanocytic skin lesions for LOH at the 1p and 9p regions.
Hussein MR, Roggero E, Tuthill RJ, Wood GS, Sudilovsky O. Identification of Novel Deletion Loci at 1p36 and 9p22-21 in Melanocytic Dysplastic Nevi and Cutaneous Malignant Melanomas. Arch Dermatol. 2003;139(6):816-817. doi:10.1001/archderm.139.6.816