[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Off-Center Fold
June 2003

A Pig Farmer With Pruritic Pink Papules and Plaques—Diagnosis

Author Affiliations


Arch Dermatol. 2003;139(6):803-808. doi:10.1001/archderm.139.6.803-a

Biopsy specimens of the skin lesions and lungs showed a granulomatous, angiocentric, angiodestructive infiltrate composed of an admixture of epithelioid histiocytes, small lymphocytes, and medium to large pleomorphic lymphocytes. Cultures of the tissue were negative for fungi, bacteria, and mycobacteria. Immunostaining of the skin and lung biopsy tissue was positive for CD45 (large anaplastic cells), CD20 (large anaplastic cells), CD3 (reactive T cells), and CD43. Taken together, the biopsy findings were consistent with a malignant lymphoma of the large-cell type with B-cell phenotype, associated with numerous reactive T cells and extensive necrosis, so-called lymphomatoid granulomatosis.

First Page Preview View Large
First page PDF preview
First page PDF preview