We read with interest the article by Voigtländer et al1 concerning the efficacy of infliximab therapy for Sneddon-Wilkinson disease, as well as the more recent report by O'Quinn and Miller2 of 2 cases of recalcitrant psoriasis that responded well to infliximab therapy. We would like to report our experience with infliximab-methotrexate combination therapy for severe pustular psoriasis of the palms and soles.
Barland C, Kerdel FA. Addition of Low-Dose Methotrexate to Infliximab in the Treatment of a Patient With Severe, Recalcitrant Pustular Psoriasis. Arch Dermatol. 2003;139(7):949-950. doi:10.1001/archderm.139.7.949