A 79-year-old white woman presented for evaluation of hyperkeratotic nodules and plaques on the lower part of her left leg. The lesions had been present for approximately 5 to 7 years. The lesions had rapidly increased in both size and number over a period of several months. A skin biopsy specimen that had been obtained at an outside institution was interpreted as well-differentiated squamous cell carcinoma (SCC), prompting the patient's referral to our institution for treatment.
Bezanis G, Wang TS, Johnson TM, Lowe L. Verrucous Plaques on the Leg—Quiz Case. Arch Dermatol. 2003;139(7):933-938. doi:10.1001/archderm.139.7.933-a