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July 2003

Dermoscopy of Melanocytic NeoplasmsSubpatterns of Dysplastic/Atypical Nevi

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Arch Dermatol. 2003;139(7):970. doi:10.1001/archderm.139.7.970

THE LESIONS shown are from the left anterior thigh of a 51-year-old white man (Figure 1), right lower abdomen of a 42-year-old white man (Figure 2), and the left upper back of a 68-year-old white man (Figure 3) (size bar, 5 mm). All 3 of these lesions reveal a relatively similar pattern. The edges have brown dots; centrally, the lesions have an opalescent quality with shades of blue and red. These lesions were histopathologically classified as "dysplastic" (atypical) nevi with severe (Figure 1), mild (Figure 2), and moderate (Figure 3) cytologic atypia. This pattern is relatively uncommon compared with other "dysplastic" nevus subtypes and likely represents a different genetic defect or different environmental influences during lesion development.

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