November 2003

Dermoscopy of Melanocytic NeoplasmsSclerotic Blue Nevi

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Copyright 2003 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2003

Arch Dermatol. 2003;139(11):1522. doi:10.1001/archderm.139.11.1522

THE LESIONS shown are from the dorsal hand of a 40-year-old white man (Figure 1), dorsal foot of a 46-year-old white man (Figure 2), and dorsal hand of a 39-year-old white man (Figure 3) (size bar, 2.5 mm). All 3 lesions reveal a relatively similar pattern. The edges of the lesions have an amorphous blue appearance (similar to blue nevi); however, the center is hypopigmented. This pattern is common in sclerotic blue nevi. Theoretically, this pattern could be caused by a clone of melanocytic cells that aberrantly proliferate and differentiate in the dermis yielding hypopigmented melanocytic cells centrally and heavily pigmented cells at the margins.

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