[Skip to Content]
[Skip to Content Landing]
Citations 0
Off-Center Fold
March 2004

Multiple Asymptomatic Nodules in an African American Boy—Diagnosis

Author Affiliations


Arch Dermatol. 2004;140(3):353-358. doi:10.1001/archderm.140.3.353-d

Light microscopic examination of the biopsy specimen revealed irregular epidermal hyperplasia associated with a dermal proliferation consisting ofaggregates of cells demonstrating a predominantly lobular growth pattern The constituent round and polyhedral cells were monotonous, with abundant eosinophilicgranular cytoplasm and distinct cell borders. Some cells demonstrated pustulo-ovoid bodies of Milian in the cytoplasm (Figure3). The nuclei were typically centrally placed, small, and often slightly hyperchromatic with inconspicuous nucleoli. Mitotic figures wereabsent.

First Page Preview View Large
First page PDF preview
First page PDF preview