The biopsy specimen from the glans penis revealed an ulcer with acute and chronic inflammation as well as cytoid bodies at the lateral margin ofthe ulcer. These findings were suggestive of lichenoid drug eruption, fixed drug eruption, or lichen planus. Following dermatology consultation, the patient'soncologist switched his chemotherapy from hydroxyurea to imatinib mesylate (Gleevec). Follow-up, 3 weeks later, revealed resolution of the penile ulceralong with improvement in the changes on the dorsal aspect of the hands.
Chronic Penile Ulceration in a 72-Year-Old Man—Diagnosis. Arch Dermatol. 2004;140(7):877-882. doi:10.1001/archderm.140.7.877-d