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December 2004

Multiple Translucent Papules on the Chest—Diagnosis

Arch Dermatol. 2004;140(12):1531-1536. doi:10.1001/archderm.140.12.1531-h

Gross examination of the biopsy specimen revealed a dermal nodule with a smooth, slightly hyperkeratotic epidermis. The cut surface was pale and translucent. Microscopic examination of a hematoxylin-eosin–stained section showed a nodule in the dermis that consisted of a mucinous matrix and a proliferation of fibroblastlike cells. The myxomatous matrix stained positively with alcian blue at a pH of 2.5 but did not contain glycogen, a finding that was confirmed by negative results on periodic acid–Schiff staining. Elastic fibers were almost absent.

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