A 69-year-old African American man with a history of severe bilateral open-angle glaucoma and blindness of his left eye dating from 1960 presented to the dermatology service for treatment of eyelid lesions in 1980. A biopsy specimen previously obtained from an atrophic erythematous plaque on the patient's cheek revealed discoid lupus erythematosus.
His ophthalmic treatment included a short course of methazolamide and a long-term course of pilocarpine ophthalmic drops in both eyes. At the initial dermatologic presentation, a course of azathioprine treatment was initiated, with resolution of the facial plaque and improvement in bilateral eyelid scarring.
Plotkin A, Alagheband M, Trevino J. Chronic Progressive Ocular Cicatrization. Arch Dermatol. 2000;136(1):113-118. doi: