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Article
April 1925

THE INTERPRETATION OF MYCOSIS FUNGOIDES AS A VARIETY OF LYMPHOSARCOMA

Author Affiliations

Instructor in Dermatology, Cornell University Medical School NEW YORK

From the Departments of Pathology and Dermatology, University and Bellevue Hospital Medical College, New York.

Arch Derm Syphilol. 1925;11(4):425-445. doi:10.1001/archderm.1925.02370040002001
Abstract

Mycosis fungoides is a term which was applied by Alibert1 to a clinical syndrome which included a group of lesions having their origin in the papillary layer of the skin. Two types of the disease were described. The first began as a diffuse dermatosis which might simulate eczema, urticaria, lichen planus or even pemphigus and ended by the formation of fungoid tumors. The second, the so-called d'emblée type, was characterized by tumor development without any previous cutaneous manifestations. The dermatoses preceding tumor development are known as prefungoid or premycotic lesions (premycosis). Histologically, these premycotic dermatoses may show evidence of the same essential changes as those found in the tumor lesions, namely, cells or groups of cells showing neoplastic features (Fig. 1). When these features are present they are characteristic, but when they are absent, as they frequently are, it is precarious to make a diagnosis based on the histologic

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