This condition was described by Biett in 1828 as erythema centrifuge; in 1845, Hebra called it seborrhoea congestiva; and in 1851, Cazenave gave it its present name, lupus erythematosus.
Since its first description, it has been the bane of dermatologists on account of its obscure causation, its resistance to treatment and its tendency to recur.
The superficial resemblance of lupus erythematosus to lupus vulgaris and the accidental accompaniment of tuberculosis in some patients suffering with lupus erythematosus, led many observers to suspect a tuberculous origin for this condition, and the extreme conservatism of medical men has made it difficult for many to get away from this idea, although positive proof of such connection has never been found.
MacLeod,1 in a most excellent review of its possible causes states:
I can not help thinking that in a certain number of the cases of lupus erythematosus which were reported to be
THRONE B. LUPUS ERYTHEMATOSUSA CLINICAL STUDY. Arch Derm Syphilol. 1925;12(1):33–40. doi:10.1001/archderm.1925.02370070046003