The frequent fatal outcome of pemphigus and the difficulties often experienced in the treatment of dermatitis herpetiformis make more than welcome any new facts which may shed light on the etiology of these conditions, and thus aid in the attainment of a cure. Within the last several years, a number of contributions have appeared which seem to lend support to some of the hypotheses advanced as explanatory of these dermatoses, and especially of pemphigus.
Let us first briefly consider the definitely known clinical and Pathologic facts relative to pemphigus, measure their relative value and then add and weigh the more recent advances. The outstanding clinical feature of all types of pemphigus is the presence of blebs which arise from apparently normal skin, the various types presenting certain differences to be considered presently. In pemphigus vulgaris, the lesions usually appear in successive crops on the cutaneous surface; they quickly develop
STRICKLER A, BROWN CP. SPINAL FLUID FINDINGS IN PEMPHIGUS AND IN DERMATITIS HERPETIFORMISWITH A NOTE RELATIVE TO THE TREATMENT OF PEMPHIGUS VEGETANS: A PRELIMINARY REPORT. Arch Derm Syphilol. 1925;12(1):48–54. doi:10.1001/archderm.1925.02370070061005