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Granuloma of Undetermined Type. Presented by Drs. MacKee and Wise.
M. H. F., aged 30, born in this country, married, had a disease which began about eight years prior to presentation, appearing as an enlarged gland in the left groin. This was removed at Mount Sinai Hospital. Section revealed a type of undetermined granuloma. About three years later, hypertrophic lesions resembling dermatitis vegetans appeared in both groins and grew rapidly. The skin over the hips became bound down and sclerotic. A stricture of the rectum had been present for about two years. Section from the rectal mucosa revealed the same type of changes as those seen from the groin sections. Destructive changes of the iliac bones and of the lateral surfaces of the lumbar vertebrae were revealed by the roentgenographic examination. There was temporary improvement of the lesions under administration of potassium iodide and of arsphenamine. Tests made for tuberculosis,
Clark AS. ATLANTIC DERMATOLOGICAL CONFERENCE: NEW YORK, NEW ENGLAND AND PHILADELPHIA DERMATOLOGICAL SOCIETIES. Arch Derm Syphilol. 1926;13(5):693–714. doi:10.1001/archderm.1926.02370170095013