The active principle of the pathogenic fungi in the skin was first isolated by Scholtz1 in 1918. Until recently the use of this extract has been limited to those who had the necessary facilities for its preparation, but since 1929, it has been obtainable from commercial laboratories. The purpose of this paper is to study, by means of the intradermal skin test, the accuracy of the product in the diagnosis of dermatomycoses of the glabrous skin.
False positive reactions of the skin are obtained in a high percentage of patients tested with extract contaminated by bacteria. Doctors Goodman and Litterer first demonstrated such results in the pathological laboratory of the Stuyvesant Square Hospital, and the fact has been fully confirmed in this series of cases. In most pseudopositive reactions, the skin responds with a marked local reaction, consisting of a large erythematous area surrounded by
WILLIAMS CM, CARPENTER CC. TRICHOPHYTIN IN DIAGNOSIS. Arch Derm Syphilol. 1932;25(5):847–851. doi:10.1001/archderm.1932.01450020873009