The abiding interest of the rosacea complex is indicated by the appearance in dermatologic literature of at least six major papers on this subject since 1920: those of Ryle and Barber,1 Lortat-Jacob and Legrain,2 W. H. Brown,3 Rulison,4 Eastwood5 and Hachenburg.6 These studies are marked seriatim by an increasing appreciation of the variety of factors involved and an increasingly searching inquiry into the mechanisms, especially the gastro-intestinal. In this paper, we aim to extend the discussion to include the psychogenic phase and to review the highly significant gastro-intestinal phase. Treatment based on the constitutional indications will then be seen to have at least the skeletal outlines of rationality.
Our study is based on eighty-three white patients observed in the private practice of one of us (J. H. S.) over a six year period, with special attention to constitutional background and history. We have
STOKES JH, BEERMAN H. EFFECT ON THE SKIN OF EMOTIONAL AND NERVOUS STATESIV. THE ROSACEA COMPLEX; A REAPPRAISAL, WITH SPECIAL REFERENCE TO THE CONSTITUTIONAL BACKGROUND AND THE RATIONALE OF TREATMENT. Arch Derm Syphilol. 1932;26(3):478–494. doi:10.1001/archderm.1932.01450030476014