Herpetologic and medical literature abounds with articles on rattlesnake bite. It has been considered from practically every standpoint. Alexander1 Anderson,2 Braddock,3 Blackwood4 and Hanley5 ably presented this subject, emphasizing especially the toxic effect of the venom when it is injected into human beings. Zozaya and Stadelman6 were the first to present a case of anaphylactic dermatitis due directly to snake venom or to emanations from poisonous reptiles. Jackson, Duke, Piness, Rowe and others reported cases of anaphylactic dermatitis, but none recorded dermatitis following rattlesnake bite. Duke dealt especially with the bites of venomous insects, such as bee stings, and considered them and the effect of their poison injected into man from the standpoint of anaphylaxis.
A colleague of mine attempted to cut down a hollow tree in which a swarm of yellow-jackets had their nest. They stung him in many places, especially around the
LOUNSBERRY CR. RATTLESNAKE ANAPHYLAXIS ASSOCIATED WITH A GENERALIZED DERMATITIS. Arch Derm Syphilol. 1934;29(5):658–667. doi:10.1001/archderm.1934.01460110016003