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Granuloma Fungoides. Presented by Dr. J. V. Klauder.
F. S., a man aged 53, presents a dermatosis of two years' duration. It began as pruritus, which was soon followed by scaly erythematous patches over the trunk, neck and extremities. Infected teeth have been removed, and the gall-bladder has been drained. A vaccine prepared from the prostatic secretion has been administered. Blood counts and chemical studies of the blood gave essentially negative results. At one hospital the patient received sixteen intraspinal injections, after which there was a temporary cessation of the severe itching. There are generalized dry, scaly, erythematous patches with ill defined borders. The arms are completely erythrodermic. In clear areas on the trunk there are moderate numbers of discrete infiltrated papules. Vesicular or bullous lesions have never occurred. Nikolsky's sign is absent. Sections show no distinctive characteristics, but their structure is compatible with the picture of granuloma fungoides,
Gilman RL, Garner VC. PHILADELPHIA DERMATOLOGICAL SOCIETY. Arch Derm Syphilol. 1935;32(3):535–540. doi:10.1001/archderm.1935.01470030177024